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Carvedilol
bulk actives (API)
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Haorui
supplies Carvedilol API (Active Pharmaceutical Ingredients) to
pharmaceutical industry. Our bulk Carvedilol
actives is produced by GMP facility.
Welcome
to contact us for product detail.
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The following information is
provided for general information purposes ONLY.
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What is Carvedilol?
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Carvedilol is a white, oval, film-coated tablet containing 3.125 mg, 6.25 mg, 12.5
mg, or 25 mg of carvedilol. Inactive ingredients
consist of colloidal silicon dioxide, crospovidone,
hypromellose, lactose, magnesium stearate, polyethylene glycol,
polysorbate 80, povidone, sucrose, and titanium dioxide.
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How does Carvedilol work?
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Carvedilol
works by relaxing the blood vessels so your heart does
not have to pump as hard.
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What is Carvedilol used for?
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Carvedilol
is used in combination with other medications to treat
heart failure. It also is used alone or in combination
with other medications to treat high blood pressure.
Carvedilol is a combination of two classes of drugs
called beta-blockers and alpha-blockers.
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Carvedilol
mode of action
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Carvedilol
comes as a tablet to take by mouth. It is usually taken
twice a day with food. You will start out taking a low
dose of carvedilol, and your doctor will increase your
dose every 1 to 2 weeks until you are taking a dose that
works well for you. When you start carvedilol and
whenever your doctor increases your dose you will be
closely watched to make sure the dose is not too high
for you. Follow the directions on your prescription
label carefully, and ask your doctor or pharmacist to
explain any part you do not understand. Take carvedilol
exactly as directed. Do not take more or less of it or
take it more often than prescribed by your doctor.
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Carvedilol
pharmacokinetics
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Carvedilol
is a nonselective β-adrenergic
blocking agent with α1-blocking activity. It is ±-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)
ethyl] amino]-2-propanol.
Carvedilol is a white
to off-white powder with a
molecular weight of 406.5 and a
molecular formula of C24H26N2O4. It
is freely soluble
in dimethylsulfoxide; soluble
in methylene chloride and methanol; sparingly soluble in 95% ethanol and isopropanol; slightly soluble
in ethyl ether; and
practically insoluble
in water, gastric fluid (simulated, TS, pH 1.1), and intestinal fluid (simulated, TS without pancreatin, pH 7.5).
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Carvedilol
side effects
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Side
effects from carvedilol can occur. Tell your doctor if
any of these symptoms are severe or do not go away:
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tiredness
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lightheadedness
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dizziness
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body
or leg swelling
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headache
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diarrhea
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vision
changes
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joint
pain
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difficulty
falling or staying asleep
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Carvedilol
Special Conditions To Observe
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Keep
this medication in the container it came in, tightly
closed, and out of reach of children. Store it at room
temperature and away from excess heat and moisture (not
in the bathroom). Throw away any medication that is
outdated or no longer needed. Talk to your pharmacist
about the proper disposal of your medication.
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Disclaimer:
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Information on
this page is provided for general information purposes.
You should not make a clinical treatment decision based
on information contained in this page without consulting
other references including the package insert of the
drug, textbooks and where relevant, expert opinion. We
cannot be held responsible for any errors you make in
administering drugs mentioned on this page, nor for use
of any erroneous information contained on this page.
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