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Clopidogrel API
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Haorui
supplies Clopidogrel API (Active Pharmaceutical Ingredients) to
pharmaceutical industry. Our bulk Clopidogrel
actives is produced by GMP facility.
Welcome
to contact us for product detail.
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The following information is
provided for general information purposes ONLY.
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What is Clopidogrel?
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Clopidogrel bisulfate
is a white to off-white
powder. It is practically insoluble in water
at neutral pH but freely soluble at pH 1. It also dissolves freely in
methanol, dissolves sparingly in methylene
chloride, and is practically insoluble in ethyl ether. It has a specific optical rotation of about +56°.
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How does Clopidogrel work?
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Clopidogrel
comes as a tablet to take by mouth. It usually is taken
once a day with or without food. To help you remember to
take clopidogrel, take it around the same time every
day. Follow the directions on your prescription label
carefully, and ask your doctor or pharmacist to explain
any part you do not understand. Take clopidogrel exactly
as directed. Do not take more or less of it or take it
more often than prescribed by your doctor.
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What is Clopidogrel used for?
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Clopidogrel
is used to prevent strokes and heart attacks in patients
at risk for these problems. Clopidogrel is in a class of
medications called antiplatelet drugs. It works by
helping to prevent harmful blood clots.
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Clopidogrel
mode of action
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Clopidogrel bisulfate is an inhibitor of A.P. induced platelet aggregation acting by
direct inhibition of adenosine diphosphate (ADP) binding to
its receptor and of the
subsequent A.P. mediated activation
of the glycoprotein GPIIb/
IIIa complex. Chemically it is methyl
(+)-( S)-a -(2- chlorophenyl)-6,7-dihydrothieno[3,2-c]
pyridine-5(4H)-acetate sulfate (1:1). The empirical formula of clopidogrel bisulfate is
C16H16Cl NO2S•H2SO4 and its molecular weight
is 419.9.
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Clopidogrel
for oral administration is
provided as pink, round, biconvex, engraved film- coated
tablets containing 97.875 mg of clopidogrel bisulfate
which is the molar equivalent of 75 mg of
clopidogrel base.
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Clopidogrel
side effects
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Clopidogrel
may cause side effects. Tell your doctor if any of these
symptoms are severe or do not go away:
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excessive
tiredness
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headache
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dizziness
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upset
stomach
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stomach
pain
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diarrhea
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constipation
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| nosebleed
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Disclaimer:
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Information on
this page is provided for general information purposes.
You should not make a clinical treatment decision based
on information contained in this page without consulting
other references including the package insert of the
drug, textbooks and where relevant, expert opinion. We
cannot be held responsible for any errors you make in
administering drugs mentioned on this page, nor for use
of any erroneous information contained on this page.
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