Gestrinone API  

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Gestrinone API

 

Haorui supplies high quality Gestrinone API produced by our GMP facility that has been successfully inspected by the FDA. We offer competitive prices and support our products with reliable technical and regulatory services.  Gestrinone API is available from R&D to commercial quantities. Please contact us for more details.

 

  The following information is provided for general information purposes ONLY.

 

What is Gestrinone?

Gestrinone is a non-estrogenic contraceptive, which is a weak progestin with strong anti-progesterone properties. It is effective if used once a week orally or can also be used in intravaginal devices.

 

How does Gestrinone work?

Gestrinone is a synthetic hormone, which acts on a part of the brain called the pituitary gland. The pituitary gland controls the levels of different types of sex hormones (oestrogen and progestogen) produced by the body. The production of the hormones is responsible for menstruation and ovulation in women. By acting on the pituitary, gestrinone decreases the production and release of these sex hormones.

Gestrinone is also thought to act directly on the endometrial tissues to prevent their growth.

 

The history of Gestrinone

Gestrinone is used to treat a condition called endometriosis, in which the tissue (endometrium) normally lining the womb grows on different organs outside the womb. The growth of this endometriotic tissue is under the influence of sex hormones. Decreasing the production of these sex hormones removes the stimulation for growth of the endometriosis.

 

Gestrinone mode of action

The first dose of this medicine must be taken on the first day of the menstrual cycle and the second dose 3 days later. Thereafter, the dose should be taken on these same 2 days of every week for the duration of treatment.

Barrier methods of contraception should be used during treatment with this medicine.

 

Gestrinone side effects

bullet Headache
bullet Depression
bullet Weight gain
bullet Alteration in results of liver function tests
bullet Retention of water in the body tissues (fluid retention)
bullet Acne
bullet Voice changes
bullet Increased hair growth (hirsutism)
bullet Nervousness
bullet Changes in sex drive
bullet Menstrual spotting between periods
bullet Reduction in breast size

 

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.    

 

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