What is Mizolastine?

Histamine may be released from and act in a small (localised) area of the body e.g the nose. Alternatively, histamine can result in a serious or complete body reaction e.g. anaphylactic reaction. Mizolastine is only useful for the prevention or relief of localised or less serious allergies such as hay fever or itchy rash (rather than very serious allergic reactions).

Mizolastine is called a non-sedating anti-histamine as it does not enter the brain in significant quantities and is therefore unlikely to cause drowsiness. However, drowsiness may very rarely occur.

How does Mizolastine work?

Mizolastine belongs to a group of medicines called non-sedating antihistamines. Histamine is a chemical produced by the body. It is stored in cells (mast cells) in almost all tissues of the body. When the body reacts to a foreign substance (an allergen e.g. flower pollen), the mast cells release their stores of histamine. Histamine may then bind to receptors (H-1 receptors) in many areas of the body causing an increase in blood flow to the area of the allergy and the release of other chemicals that add to the allergic response. This stimulates the symptoms of an allergic reaction such as inflammation of the skin, airways or tissues, rashes, itching of the skin, eyes or nose, nasal congestion or narrowing of the airways. Mizolastine acts by blocking the binding of histamine to receptors in the body. It does not prevent the actual release of histamine from mast cells. By blocking the binding of histamine, the release of other chemicals and increased blood supply to the area is prevented or decreased. This results in prevention or relief of the typical symptoms of an allergic reaction.

What is Mizolastine used for?

Inflammation of the nasal lining and surface of the eye(s) occurring year-round due to allergies (perennial allergic rhinoconjunctivitis)

Allergic, itchy skin rash (urticaria)

Inflammation of the nasal lining and surface of the eye(s) due to allergies occurring only in particular seasons of the year (seasonal allergic rhinoconjunctivitis/hay fever)

Mizolastine side effects

Headache ; Dry mouth ;Diarrhoea ; Drowsiness ; Abnormal heart beats (arrhythmias);Indigestion (dyspepsia) ;Weakness or loss of strength

Mizolastine Special Conditions To Observe

This medicine may reduce your ability to drive or operate machinery safely. Do not drive or operate machinery until you know how this medicine affects you and you are sure it won't affect your performance.

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.