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Paroxetine
HCl API
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Haorui
supplies Paroxetine HCl API (Active Pharmaceutical Ingredients) to
pharmaceutical industry. Our bulk Paroxetine
HCl actives is produced by GMP facility.
Welcome to contact us for
product detail.
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The following information is
provided for general information purposes ONLY.
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What is Paroxetine?
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Paroxetine hydrochloride is an orally administered
psychotropic drug. It is the hydrochloride salt of a phenylpiperidine compound
identified chemically as
(-)-trans-4R-(4'-fluorophenyl)-3S-[(3',4'-methylenedioxyphenoxy)
methyl] piperidine hydrochloride
hemihydrate and has the empirical formula of C19H20FNO3·HCl·1/2H2O. The
molecular weight is 374.8 (329.4 as
free base).
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How does Paroxetine work?
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Paroxetine
tablets, suspension (liquid) and extended-release
(long-acting) tablets are used to treat depression,
panic disorder (sudden, unexpected attacks of
extreme fear and worry about these attacks), and
social anxiety disorder (extreme fear of interacting
with others or performing in front of others that
interferes with normal life). Paroxetine tablets and
oral solution are also used to treat obsessive
compulsive disorder (bothersome thoughts that won't
go away and the need to perform certain actions over
and over), generalized anxiety disorder (excessive
worrying that is difficult to control), and
posttraumatic stress disorder (disturbing
psychological symptoms that develop after a
frightening experience). Paroxetine extended-release
tablets are also used to treat premenstrual
dysphoric disorder (PMDD, physical and psychological
symptoms that occur before the onset of the
menstrual period each month). Paroxetine is in a
class of medications called selective serotonin
reuptake inhibitors (SSRIs). It works by increasing
the amount of serotonin, a natural substance in the
brain that helps maintain mental balance.
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Paroxetine
mode of action
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Paroxetine
comes as a tablet, a suspension (liquid), and a
controlled-release (long-acting) tablet to take by
mouth. It is usually taken once daily in the morning
or evening, with or without food. You may want to
take paroxetine with food to stop it from upsetting
your stomach. To help you remember to take
paroxetine, take it around the same time every day.
Follow the directions on your prescription label
carefully, and ask your doctor or pharmacist to
explain any part you do not understand. Take
paroxetine exactly as directed. Do not take more or
less of it or take it more often than prescribed by
your doctor.
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Swallow
the extended-release tablets whole; do not split,
chew, or crush them.
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Shake
the liquid well before each use to mix the
medication evenly.
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Paroxetine
pharmacokinetics |
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Each film-coated tablet contains paroxetine hydrochloride
equivalent to paroxetine as follows: 10 mg–yellow
(scored); 20 mg–pink (scored); 30 mg–blue, 40
mg–green. Inactive ingredients consist of dibasic calcium phosphate
dihydrate, hypromellose, magnesium stearate, polyethylene
glycols, polysorbate 80, sodium starch glycolate, titanium dioxide, and 1 or more of the following: D&C Red
No. 30, D&C Yellow No. 10, FD&C Blue No. 2,
FD&C Yellow No. 6.
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Paroxetine
side effects
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Paroxetine
may cause side effects. Tell your doctor if any of
these symptoms are severe or do not go away:
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headache
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dizziness
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weakness
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difficulty
concentrating
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nervousness
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forgetfulness
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confusion
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sleepiness
or feeling "drugged"
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difficulty
falling asleep or staying asleep
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upset
stomach
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vomiting
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diarrhea
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constipation
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gas
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stomach
pain
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heartburn
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changes
in ability to taste food
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decreased
appetite
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| weight
loss or gain
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Disclaimer:
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Information on this page is provided for
general information purposes. You should not make a
clinical treatment decision based on information
contained in this page without consulting other
references including the package insert of the drug,
textbooks and where relevant, expert opinion. We
cannot be held responsible for any errors you make
in administering drugs mentioned on this page, nor
for use of any erroneous information contained on
this page.
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