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Pravastatin Sodium API |
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Haorui supplies Pravastatin Sodium API
(Active
Pharmaceutical Ingredients) to pharmaceutical
industry. Our bulk Pravastatin Sodium actives are produced
by GMP facility.
Welcome to contact us for
product detail. |
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The following information is provided for
general information purposes ONLY. |
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What is Pravastatin Sodium?
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Pravastatin sodium is designated chemically as
1-Naphthalene-heptanoic acid, 1,2,6,7,8,8a-hexahydro-b,d
,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, monosodium
salt, [1S-[1a(bS*,dS*),2a,6a,8b(R*),8aa]]-. |
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Pravastatin
Sodium Chemical Structure |
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What is Pravastatin Sodium used for? |
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Pravastatin sodium is one of a class of lipid-lowering
compounds, the HMG-CoA reductase inhibitors, which reduce
cholesterol biosynthesis. These agents are competitive
inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)
reductase, the enzyme catalyzing the early rate-limiting
step in cholesterol biosynthesis, conversion of HMG-CoA to
mevalonate. |
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Pravastatin is used with diet changes (restriction of
cholesterol and fat intake) to reduce the amount of
cholesterol and certain fatty substances in the blood.
Pravastatin is in a class of medications called HMG-CoA
reductase inhibitors (statins). It works by slowing the
production of cholesterol in the body. Buildup of
cholesterol and fats along the walls of the blood vessels (a
process known as atherosclerosis) decreases blood flow and,
therefore, the oxygen supply to the heart, brain, and other
parts of the body. Lowering blood levels of cholesterol and
fats may help to prevent heart disease, angina (chest pain),
strokes, and heart attacks. |
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Precautions Before Using Pravastatin
Sodium |
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Before
taking pravastatin,
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tell your doctor and pharmacist if you are allergic to
pravastatin or any other medications. |
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tell your doctor and pharmacist what prescription and
nonprescription medications, vitamins, nutritional
supplements, and herbal products you are taking. Be sure
to mention any of the following: cimetidine; erythromycin;
ketoconazole; medications that suppress the immune system
such as cyclosporine; other cholesterol-lowering
medications such as fenofibrate, gemfibrozil, and niacin;
and spironolactone. Your doctor may need to change the
doses of your medications or monitor you carefully for
side effects. |
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if you are taking cholestyramine or colestipol, take them
4 hours before or 1 hour after pravastatin. |
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tell your doctor if you drink large amounts of alcohol and
if you have or have ever had liver or kidney disease.
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tell your doctor if you are pregnant, plan to become
pregnant, or are breast-feeding. If you become pregnant
while taking pravastatin, stop taking pravastatin and call
your doctor immediately. Pravastatin may harm the fetus.
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if you are having surgery, including dental surgery, tell
the doctor or dentist that you are taking pravastatin.
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if you have a severe infection, surgery, an injury, low
blood pressure, or seizures while taking pravastatin, talk
to your doctor about stopping to take the medication for a
while. |
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Pravastatin Sodium side effects
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Pravastatin may cause side effects. Tell your doctor if
either of these symptoms is severe or does not go away:
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heartburn |
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headache |
Some side
effects can be serious. The following symptoms are uncommon,
but if you experience any of them, call your doctor
immediately:
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muscle pain, tenderness, or weakness |
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lack of energy |
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fever |
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yellowing of the skin or eyes |
Pravastatin may cause other side effects. Call your doctor
if you have any unusual problems while taking this
medication. |
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What should you do if you miss a dose of
Pravastatin Sodium? |
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Take the
missed dose as soon as you remember it. However, if it is
almost time for the next dose, skip the missed dose and
continue the regular dosing schedule. Do not take a double
dose to make up for a missed one. |
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Overdose Pravastatin Sodium |
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In case
of overdose, call your local poison control center at
1-800-222-1222. If the victim has collapsed or is not
breathing, call local emergency services at 911. |
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Pravastatin Sodium Storage |
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Keep this
medication in the container it came in, tightly closed, and
out of reach of children. Store it at room temperature and
away from excess heat and moisture (not in the bathroom).
Throw away any medication that is outdated or no longer
needed. Talk to your pharmacist about the proper disposal of
your medication. |
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Disclaimer:
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Information on this page is provided for
general information purposes. You should not make a clinical
treatment decision based on information contained in this
page without consulting other references including the
package insert of the drug, textbooks and where relevant,
expert opinion. We cannot be held responsible for any errors
you make in administering drugs mentioned on this page, nor
for use of any erroneous information contained on this
page. |
