Granisetron HCl

CAS: 107007-99-8 
BP/EP/USP
USDMF No. 19365, USFDA  Approved
CEP: R1-CEP 2009-341-Rev03, UK GMP
Stability Studies In Zone IVB.
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Technical Data

M. Wt

348.88

Molecular Formula

C18H25ClN4O

CAS Number

107007-99-8

PubChem ID

65264

InChI Key

QYZRTBKYBJRGJB-UHFFFAOYSA-N

Smiles

O=C(C3=NN(C)C4=C3C=CC=C4)NC1CC(N2C)CCCC2C1.Cl

Documents

USDMF No. 19365, USFDA Approved
CEP: R1-CEP 2009-341-Rev03, UK GMP
Stability Studies In Zone IVB.

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

 

Description

Granisetron Hydrochloride is the hydrochloride salt of an indazole derivative with antiemetic properties. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.

 

Synonym

Kytril; C18H24N4O.HCl; Kytril Injection; 1-Methyl-N-(9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl)-1H-Indazole-3-Carboxamide Hydrochloride

 

Disclaimer

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1). 

GranisetronHCl